7. Bhargava KP, Singh N. Anti-stress activity of Ocimum sanctum Linn. Indian J Med Res. 1981 March; 73: 443-451.
Universitet, Moscow, USSR ; Fiziologicheskii Zhurnal SSSR ISSN 0015-329X ; , vol. 74, Nov. 1988, p. 1580-1587. In Russian. refs A89-30075 BEHAVIORAL AND METABOLIC CHARACTERISTICS IN SPONTANEOUSLY HYPERTENSIVE RATS [POVEDENCHESKIE I METABOLICHESKIE OSOBENNOSTI SPONTANNO GIPERTENZIVNYKH KRYSI A. A. BACHMANOV, IU. S. DMITRIEV, and L. S. MASLENNIKOVA AN SSSR, lnstitut Fiziologii, Leningrad, USSR ; Fiziologicheskii Zhurnal SSSR ISSN 0015-329X ; , vol. 74, Nov. 1988, p. 1677-1683. In Russian. refs ' The behavioral patterns of spontaneously hypertensive SHR-line ; rats were compared with those of normotensive Wistar rats. It was found that, in the hypertensive rats, the overall daily activity, the activity associated with alternating illumination, and the behavioral activity associated with exploratory motivation were higher, whereas the activity associated with fear motivation was lower. The 20-week-old SHR rats also had a higher total oxygen consumption and lower p02 and blood circulation velocity in the sensomotor area of the brain than the normotensive rats. On the other hand, at 12 weeks of age, no difference in oxygen metabolism was found, indicating that the decreases in the oxygen supply appearing at 20 weeks are not related to behavioral changes I.S. occurring at the early stages of hypertension. A89-30181 MODULATING THE FAST-MUSCLE-FIBER RESTING POTENTIAL WITH ALPHA-TOCOPHEROL IN RATS ADAPTED TO COLD [MODULIROVANIE ALPHA-TOKOFEROLOM MEMBRANNOGO POTENTSIALA POKOIA BYSTROGO MYSHECHNOGO VOLOKNA KRYSY PRI ADAPTATSII K KHOLODU] G. P. BELOUSOVA Petrozavodskii Gosudarstvennyi Universitet, Petrozavodsk, USSR ; Fiziologicheskii Zhurnal SSSR ISSN 0015-329X ; , vol. 74, Oct. 1988, p. 1476-1479. In Russian. refs The effect of an antioxidant alpha-tocopherol ; on the resting membrane potential RMP ; of fast muscle fibers during adaptation to cold was investigated in rats kept at -1 to -15 C for four weeks. Alpha-tocopherol 50 mg kg ; was injected to room-temperature controls and to one group of adapted animals every other day for 4 weeks; the other group was also preinjected before cold exposure ; with tocopherol. The RMP was measured in situ by intracellularly inserted microelectrodes. It was found that rats subjected to a cold environment exhibited lower by about 11.7 mv ; values of RMP, indicating that tocopherol promotes the stabilization of muscle membranes. I.S. A89-30240 EXPERIMENTAL PROOF OF THE EXISTENCE OF A PARALLEL DOUBLE DNA HELIX [EKSPERIMENTAL'NOE DOKAZATEL'STVO SUSHCHESTVOVANIIA PARALLEL'NOI DVOlNOl SPIRAL1 DNK] A. K. SHCHELKINA, IU. P. LYSOV, I. A. IL'ICHEVA, A. A. CHERNYI, IU. B. GOLOVA AN SSSR, lnstitut Molekuliarnoi Biologii, Moscow, USSR ; et al. Akademiia Nauk SSSR, Doklady ISSN 0002-3264 ; , vol. 304, no. 2, 1989, p. 476-480. In Russian. refs It is demonstrated experimentally that oligodeoxyribonucleotides consisting of natural monomeric units can form a double helix with a parallel arrangement of links under conditions close to physiological ones. The thermodynamics of the formation of the parallel structure is examined, and spectra of the parallel structure are presented. B.J. A89-30241 EFFECT OF HYPERTHERMIA ON THE SYNTHESIS OF CATECHOLAMINES IN ISOLATED ORGANS [EFFEKT GlPERTERMll NA SINTEZ KATEKHOLAMINOV V IZOLIROVANNYKH ORGANAKH] B. N. MANUKHIN, KH. A. MEZIDOVA, B. K. SHAIYMOV, and F. F. SULTANOV AN SSSR, lnstitut Biologii Razvitiia, Moscow, USSR; AN TSSR, lnstitut Fiziologii i Eksperimental'noi Patologii Aridnoi.
Fig. 1. The outcome of 124 patients treated with LADR is shown. Fifty-seven patients 46% ; experienced on-treatment virological clearance EOTR 67 were nonresponders. Thirty patients 24% ; were HCV RNAnegative at last follow-up. LADR, low accelerating dosage regimen; HCV, hepatitis C virus; EOTR, end of treatment; SVR, sustained virological response; NR, nonresponders.
The Federation of State Medical Boards' Model Policy for the Use of Controlled Substances for the Treatment of Pain recommends that special attention, such as monitoring, documentation, and consultation referral, should be given to patients who are at risk for misusing medications eg, history of substance misuse or addiction, comorbid psychiatric disorder ; .25 Unexpected positive or negative UDT results are useful to suggest and support a decision to refer a patient to a specialist experienced in treating patients with complex conditions, such as a pain management specialist who is knowledgeable in addiction medicine.17, 25.
Throughout your life, your allergic sensitivity fluctuates. It can be increased following exposure to pollens in the springtime, or if you have recently developed symptoms after being in a mouldy place, or if you have recently had an asthma exacerbation. This may have happened to you and the new sensitivity to this perfume could be temporary and gradually resolve. You may find however that you can no longer use this perfume.
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Man Ki Ho, Hon B . * , Rachel F. Tyndale, Ph.D., University of Toronto, Ontario, Canada; Margaret R. Spitz, M.D., Melissa Bondy, Ph.D., Anna Wilkinson, Ph.D., The University of M.D. Anderson Cancer Center, Houston, Texas Hispanics are an understudied and poorly represented group in health research despite their substantial and growing numbers in the United States. Specifically, Hispanics have unique smoking patterns; compared to non-Hispanic whites, they tend to have lower smoking prevalence, smoke fewer cigarettes per day and have a lower risk of lung cancer. Genetic variations in human CYP2A6, encoding the enzyme that converts most of nicotine ~90% ; to its inactive metabolite cotinine, alter nicotine metabolism and thus smoking behaviors. Genetic variations in CYP2B6 have also been implicated in smoking behaviors, with the CYP2B6 * 6 allele associated with increased progression to nicotine dependence in adolescents and lower abstinence rates. The objective of this study was to characterize the genetic variation in CYP2A6 and CYP2B6 in a Hispanic population. Male subjects n 200 ; recruited from a longitudinal Mexican-American cohort established in the Houston metropolitan area were selected. Current smokers n 100 ; and former smokers n 100 ; who have maintained abstinence for at least one year were selected and stratified by smoking duration 10-25 years or 25 years ; . Using a two-step allele-specific genotyping assay, the allele frequencies were found at 2.5% 95% confidence interval 1.0 - 4.0% ; for CYP2A6 * 2, 0.3% 0 - 0.7% ; for CYP2A6 * 4, 10.5% 7.5 - 13.5% ; for CYP2A6 * 9 and 2.8% 1.1 - 4.4% ; for CYP2A6 * 12, which are similar to previously reported values in non-Hispanic whites. The CYP2A6 * 7 allele, which occurs mainly in Asians, was not detected although CYP2A6 * 17, which occurs mainly in African-Americans, was found at an allele frequency of 1.5% 0.3 - 2.7% ; . CYP2B6 * 6 was found at an allele frequency of 31.3% 26.7 - 35.8% ; compared to previously reported values of 25% in non-Hispanic whites, 30% in African-Americans, and 15% in Asians. Thus, the genetic variation in CYP2A6 and CYP2B6 in this Mexican-American population is similar to non-Hispanic whites, with some suggestion of African-American ancestry. Future analyses will be done to determine whether CYP2A6 and CYP2B6 genetic variations are associated with smoking status, smoking duration, and cigarette consumption. This study was supported by CIHR grant MOP53248 and a CRC RFT ; , an NSERC CGS-D Postgraduate Scholarship MKH ; , and CA105203 MRS ; . CORRESPONDING AUTHOR: Manki Ho, Hon. B ., Graduate Student, University of Toronto, Pharmacology, Rm. 4326, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; tel: 416-978-4082; email: manki.ho utoronto.
The September issue of the Journal of the American Medical Association 2003; 290[10]: 1299-1303 ; featured a disquieting article titled "Addiction Poorly Understood by Clinicians." "For all the lip service paid to the concept of addiction as a medical disease, the idea has yet to gain traction with a large proportion of physicians, " wrote Brian Vastag. addiction, is Addiction Treatment Forum. Share your copy with healthcare colleagues or direct them to : atforum and ismo.
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If you don't join a Medicare drug plan when you are first eligible, and you go without creditable prescription drug coverage as good as Medicare's ; for 63 continuous days or more, you may have to pay a late enrollment penalty to join a plan later. This penalty amount changes every year, and you will have to pay it as long as you have Medicare prescription drug coverage. However, if you qualified for extra help in 2006 and or 2007, you may not have to pay a penalty. If you must pay a late enrollment penalty, your penalty is calculated when you first join a Medicare drug plan. To estimate your penalty, take 1% of the national base beneficiary premium for the year you join in 2007, the national base beneficiary premium is .35 ; . Multiply it by the number of full months you were eligible to join a Medicare drug plan but didn't, and then round that amount to the nearest ten cents. This is your estimated penalty amount, which is added each month to your Medicare drug plan's premium for as long as you are in that plan. If you disagree with your late enrollment penalty, you may be eligible to have it reconsidered reviewed ; . Call Customer Service to find out more about the reconsideration process and how to ask for such a review.
All product or service marks appearing in type form different from that of the surrounding text are trademarks or service marks owned by or licensed to Merck & Co., Inc., its subsidiaries or affiliates. Cozaar and Hysaar are registered trademarks of E.I. du Pont de Nemours and Company, Wilmington, Delaware, USA. Zetia and Vytorin are trademarks owned by an entity of the Merck Schering-Plough Pharmaceuticals partnership. Claritin is a trademark of Schering Corporation. Prilosec and Nexium are trademarks of the AstraZeneca group. The U.S. trademarks for Vasotec and Vaseretic are owned by Biovail Laboratories Incorporated. The U.S. trademark for Aggrastat is owned by Guilford Pharmaceuticals Inc and imdur.
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83 [Slide.] As Dr. Waclawski mentioned, control rates in Study 176 were higher than previously shown in the Jyzaar program. This difference was associated with a very large difference in mean blood pressure reductions. Avalide in Study 176 lowered blood and avapro.
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Also sponsors defined contribution plans and participates in government-sponsored programs in certain countries. On June 30, 2000, the German operations of the Company terminated a defined benefit pension plan and replaced it by a new benefit concept. Benefit accruals for all eligible employees were frozen as of that date. Vested pension benefits from the old plan will be paid after the retirement requirements of the plan are met. Commencing July 1, 2000, a defined benefit pension plan was created in Germany covering substantially all employees. The plan has been instituted through a collective benefit fund that is an independent organization. The fund is committed to purchase reinsurance annuity contracts for every individual participant in order to secure future retirement payments from the fund to those participants. The Company contributes 0.75% of every participant's eligible salaries wages to the plan contribution 1 ; . The participant may elect to contribute certain amounts not to exceed 0.75% of their eligible salaries wages to the plan contribution 2 ; . The Company will match the employee's election contribution 2 only ; up to the elected amount but not to exceed the predetermined maximum. In addition, the participants may further contribute at their discretion up to 0.75% of their eligible salaries wages to the plan contribution 3 ; . All contributions to the plan are vested immediately. The accumulated benefit obligation will generally be settled through lump-sum distributions at the time of retirement based on actuarial evaluations. The amount of the pension payment is determined based on the actuarial calculation of the respective contribution to the pension as part of the reinsurance. The participant may elect to spread such distributions over up to five partial payments. In 2002, the existing benefit pension plan of the German operations was modified. Henceforth, there are two different models for both standard wage employees and sales force representatives and management. For standard wage and sales force employees the company contributes 0.75% of every participant's eligible salaries wages to the plan contribution 1 ; . In addition, the employees can use the employer's contribution for tax deductible savings plans "Vermgenswirksame Leistungen" ; to contribute to the plan contribution 2 ; . The Company will match the employee's election contribution 2 only ; up to the elected amount but not to exceed the predetermined maximum. If contribution 2 was paid, the participants may elect to renounce payment of certain or all parts of their vacation bonus and contribute the amount to the plan contribution 3 ; . Contribution 3 is added up by the Company with 13% of the participant's expended vacation bonus. Only if contribution 3 is completely exhausted, an additional amount can be converted within the scope of year-end bonus payment contribution 4 ; . All contributions to the plan are vested immediately and tenormin.
Or offset of episodes of depression and mania 6, 7 ; . Thus, it is reasonable to suggest that developmental alcohol exposure produces abnormalities in circadian rhythms that may contribute to the development of seasonal and nonseasonal mood disorders. Circadian rhythm abnormalities are one of many harmful effects of developmental alcohol exposure.
A 3-generation study on the toxic effects of resmethrin on reproduction in rats revealed statistically significant effects of treatment on the number of stillborn pups per litter and on weight gains of pups during weaning. The lowest dose level that caused an effect was 25 mg kg day, the lowest level tested. This study, considered to be of quality, was used to determine the igh reference dose level of 0.03 mg kg day and lipitor.
The child was sedated and chemically paralyzed. A size four, uncuffed endotracheal tube was placed and secured at 13 cm. at the gums. Phenobarbital 200 mg. IV was administered for seizure treatment and prophylaxis. Ceftriaxone 500 mg. was administered IV for possible sepsis. The child was sent to the imaging area for CT scan of the brain.
The GAO's poll results included the responses of sixty-seven medical researchers who rated their confidence in aspartame as a harmless food additive. Only twelve of the sixty-seven researchers who responded to the safety question and aceon.
1. American Gastroenterological Association. The Burden of Gastrointestinal Diseases. Bethesda, Md: American Gastroenterological Association; 2001: 1-86. Available at: : gastro clinicalRes pdf burden-report . Accessed November 16, 2004. 2. Frank L, Kleinman L, Rentz A, Ciesla G, Kim JJ, Zacker C. Health-related quality of life associated with irritable bowel syndrome: comparison with other chronic diseases. Clin Ther. 2002; 24: 675-689. Gralnek IM, Hays RD, Kilbourne A, Naliboff B, Mayer EA. The impact of irritable bowel syndrome on health-related quality of life. Gastroenterology. 2000; 119: 654-660.
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Operating Results Sales Worldwide sales for 2003 increased 5% in total over 2002, reflecting a 4% favorable effect from foreign exchange and a 1% favorable effect from price changes. The overall increase reflects strong growth of Singulair for asthma and seasonal allergic rhinitis, Fosamax for osteoporosis, and Cozaar Hyzaae for high blood pressure. Also contributing to the increase were sales of Vioxx and Arcoxia for arthritis and pain, Cancidas for infections, Cosopt for glaucoma, Proscar for benign prostate enlargement, and Maxalt for migraines. Revenues from the Company's relationship with AstraZeneca LP AZLP ; also added to the overall growth. Domestic sales increased by 1%, while foreign sales grew 11%. Sales in the United States were unfavorably impacted by the implementation of a new distribution program for U.S. wholesalers as described below, and foreign sales were negatively affected by the loss of basic patent protection for Zocor, for modifying cholesterol, in Canada and certain countries in Europe, including the United Kingdom and Germany. Foreign sales represented 41% of total sales in 2003. Historically, in anticipation of possible price increases, certain U.S. wholesalers placed some noncancellable orders at prices that remained in effect until Merck shipped the product. In the fourth quarter of 2003, the Company implemented a new distribution program for U.S. wholesalers to moderate the fluctuations in sales caused by wholesaler investment buying and improve efficiencies in the distribution of Merck pharmaceutical products. The new program has lowered previous limits on average monthly purchases of Merck pharmaceutical products by U.S. customers. Overall, implementation of the new U.S. wholesaler distribution program had an estimated 0 to 0 million unfavorable impact on consolidated revenues with an estimated 0 million unfavorable effect on Zocor sales. Worldwide sales for 2002 increased 1% in total and 2% on a volume basis from 2001. Foreign exchange had less than a one-half point unfavorable effect on sales growth and price changes had essentially no effect on growth. Foreign sales represented 39% of total sales in 2002. Sales 1 ; by category of the Company's products were as follows: $ in millions ; Atherosclerosis Hypertension heart failure Anti-inflammatory analgesics Osteoporosis Respiratory Vaccines biologicals Anti-bacterial anti-fungal Ophthalmologicals Urology Human immunodeficiency virus HIV ; Other and aldactone.
Dean Health Plan Formulary cont' Therapeutic Interchange List Note: Suggested interchange is product appropriate for MOST indications. Last Updated * 10 24 2006 Non-Preferred Not Covered Alternative * FLOMAX doxazosin terazosin UROXATRAL fluvoxamine citalopram fluoxetine LEXAPRO paroxetine sertraline methylphenidate FOCALIN FROVA AMERGE IMITREX MAXALT ZOMIG GLUCOPHAGE metformin GLUCOPHAGE XR metformin ER guaifenesin pseudoephedrine products OTC equivalents GYNE-LOTRIMIN 3 OTC Alternatives GYNODIOL estradiol HALFLYTELY BOWEL PREP KIT peg 3350 electrolytes trilyte HALOG betamethasone triamcinolone HELIDAC metronidazole + tetracycline + bismuth HISTA-VENT DA OTC Alternatives HISTEX PD OTC Alternatives HUMALOG NOVOLOG HUMALOG MIX NOVOLOG MIX HUMULIN NOVOLIN hydroquinone cr. Not Covered ; Plan Exclusion HYZAAR ATACAND HCT AVALIDE DIOVAN HCT INSULIN SYRINGES PRECISION BRAND IPLEX Not Covered ; INCRELEX ISMO isosorbide mononitrate ISOPTIN SR ; verapamil verapamil SR K-LYTE potassium KADIAN morphine sulfate morphine sulfate ER KEFLEX cephalexin KEFTAB cephalexin KETEK amoxicillin amoxicillin clav azithromycin tabs BIAXIN XL ketoprofen regular release diclofenac ketoprofen ER ibuprofen indomethacin.
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Pramlintide acetate injection Symlin ; diabetes in conjunction with insulin - a synthetic analog of human amylin that is given subcutaneously. Amylin is a neuroendocrine hormone secreted by the beta cells of the pancreas and is co-secreted with insulin in response to food intake. This drug works by delaying gastric emptying, preventing postprandial glucagon rise, and producing satiety.
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Patients within the community setting, including those being managed in their own homes present a lower risk of spread of MRSA as they are less like to be seriously ill, to have an indwelling device or to come into contact with other vulnerable persons. However, patients being managed by community nursing staff and other healthcare professionals ; should be cared for applying the same basic standard infection control precautions in order to minimise the risk of spread to other patients being managed by the care team. In some cases e.g. patients with colonised wounds and those requiring high levels of nursing intervention, it may be appropriate to care for these patients at the end of the working day is this is feasible Patients in primary care attending local services such as GP surgeries, health centres etc. will be managed in accordance with local protocols which generally include the application of standard infection control precautions. This includes the wearing of appropriate protective clothing, environmental and equipment cleaning, management of clinical waste and the application of robust hand decontamination protocols. On some occasions e.g. when attending leg ulcer clinics it may be appropriate to attend to MRSA positive patients at the end of a clinic list to allow adequate time for environmental equipment cleaning after the case be undertaken on an individual patient basis. The needs of the patient must be balanced against the possible risk of spread and the need to provide all In PCT intermediate and continuing care facilities a risk assessment should patients with the level and standard of care that is required to meet their full expectations of recovery. Patients attending hospital either as outpatients or for admission may pose a risk of cross-infection. It is essential that PCT staff inform the receiving department if a patient is known to be colonised with MRSA.
DIN GP Brand Name Generic Name ATC Dosage Form Comments FROSST CANADA & CO. Continued ; 00587699 00576131 02233055 DOLOBID - 250mg TAB DOLOBID - 500mg TAB FOSAMAX - 5mg TAB FOSAMAX - 10mg TAB FOSAMAX - 40mg TAB HEPTAVAX-B HYZAAR 50 12.5 INDOCID-SR - 75mg CAP M-M-R II MEFOXIN ADD-VANTAGE - 1000mg VIAL MEFOXIN ADD-VANTAGE - 2000mg VIAL MEVACOR - 10mg TAB MEVACOR - 20mg TAB MEVACOR - 40mg TAB NOROXIN - 3mg ml NOROXIN - 400mg TAB PEDVAXHIB PEPCID - 8mg ml PEPCID - 10mg ml PEPCID - 20mg TAB PEPCID - 40mg TAB PNEUMOVAX 23 PRIMAXIN 250 PRIMAXIN 250 ADD-VANTAGE PRIMAXIN 500 PRIMAXIN 500 ADD-VANTAGE PRIMAXIN IM 500 PRIMAXIN IM 750 PRINIVIL - 5mg TAB PRINIVIL - 10mg TAB PRINIVIL - 20mg TAB PRINIVIL - 40mg TAB PRINIVIL - 80mg TAB PRINZIDE 10 12.5 PRINZIDE 20 12.5 PRINZIDE 20 25 PROPECIA - 1mg TAB PROSCAR - 5mg TAB RECOMBIVAX HB - 0.01mg ml RECOMBIVAX HB - 0.04mg ml SINGULAIR - 5mg TAB SINGULAIR - 10mg TAB diflunisal diflunisal alendronate sodium alendronate sodium alendronate sodium vaccine - hepatitis B losartan potassium hydrochlorothiazide indomethacin vaccine - measles mumps rubella cefoxitin sodium cefoxitin sodium lovastatin lovastatin lovastatin norfloxacin norfloxacin vaccine - Hemophilus influenzae B famotidine famotidine famotidine famotidine vaccine - polyvalent pneumoccocal imipenem cilastatin sodium imipenem cilastatin sodium imipenem cilastatin sodium imipenem cilastatin sodium imipenem cilastatin sodium imipenem cilastatin sodium lisinopril lisinopril lisinopril lisinopril lisinopril lisinopril hydrochlorothiazide lisinopril hydrochlorothiazide lisinopril hydrochlorothiazide finasteride finasteride vaccine - hepatitis B rDNA ; vaccine - hepatitis B rDNA ; montelukast sodium montelukast sodium N02BA N02BA M05BA M05BA M05BA J07BC C09DA M01AB J07BD J01DA J01DA C10AA C10AA C10AA S01AX J01MA J07AG A02BA A02BA A02BA A02BA J07AL J01DH J01DH J01DH J01DH J01DH J01DH C09AA C09AA C09AA C09AA C09AA C09BA C09BA C09BA G04CB G04CB J07BC J07BC R03DC R03DC tablet tablet tablet tablet tablet injectable suspension tablet sustained-release capsule injectable suspension powder for injectable solution powder for injectable solution tablet tablet tablet ophthalmic solution tablet injectable suspension oral suspension injectable solution tablet tablet injectable suspension powder for injectable solution powder for injectable solution powder for injectable solution powder for injectable solution powder for injectable solution powder for injectable solution tablet tablet tablet tablet tablet tablet tablet tablet tablet tablet injectable suspension injectable suspension chewable tablet tablet not sold.
2. Route of Administration. Determine the Route of Administration RA ; used to administer each medication. The MAR and the physician's orders should identify the RA for each medication. Record the RA in column 2 using the following codes: 1 by mouth PO ; 5 subcutaneous SQ ; 2 sub lingual SL ; 6 rectal R ; 3 intramuscular IM ; 7 topical 4 intravenous IV ; 8 inhalation 9 enteral tube 10 other.
We have come to prefer a world where the distractible take Ritalin, the depressed take Prozac, and the unattractive get cosmetic surgery to a world ruled, arbitrarily, by those fortunate few who were born focused, happy and beautiful. Cosmetic surgery is not "earned" beauty, but then natural beauty isn't earned, either. One of the principal contributions of the late twentieth century was the moral deregulation of social competition--the insistence that advantages derived from artificial and extraordinary intervention are no less legitimate than the advantages of nature. All that athletes want, for better or worse, is the chance to play by those same rules. Emphasis added.
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